Description
The Shasta Synthesizer – Ultra-Efficient Oligo Production That Scales
The Shasta Synthesizer is engineered for high-output labs demanding flexibility, reliability, and minimal downtime. Its patented hardware, user-friendly software, and robust safety certifications reduce labor and deliver higher yields with faster turnarounds. The Shasta supports applications from high-throughput screening to large-scale production.
Key Features
Scalable Design: Adapts to small-scale assays or 100umol+ scale oligo production, growing with your lab’s needs.
Unified Platform: Supports ultra-high throughput screening, custom method development, and large-scale synthesis without protocol migration.
Enhanced Efficiency: Patented technology boosts coupling efficiency, minimizing reagent waste and maximizing output.
Intuitive Software: Streamlines workflow management, reducing manual intervention and errors.
Stock Protocols: Ready-made protocols to get you started on day one.
Safety Certified: Meets rigorous lab standards for reliable, secure operation.
The Shasta Synthesizer eliminates the need for multiple systems, providing a single, versatile solution for high-throughput labs aiming for precision, scalability, and speed.
Patented Selective Drain System – Speed Meets Control
Unlike alternative systems, Shasta’s Selective Drain System allows users to:
- Drain rows or columns individually
- Skip finished wells—no wasted reagents due to sequence variability
- Minimize drain times by isolating only what’s needed
The result: shorter runs, reduced solvent usage, and greater consistency.
Standard Features
- 24 Amidite + 8 Reagent Positions
- Kalrez® & PTFE seals throughout
- Full Software with No License Fees
- Up to 10 Backbone Modifications
- Amidite-Specific Handling
- Includes installation, training, and 1-year warranty
Approvals
- UL 61010-1
- cUL 61010-1-12
- CE, EMC Directive 2014/30/EU
- CE, LVD Directive 2014/35/EU
White Paper
768 Module – For the Highest Throughput Needs
The Shasta 768 module is designed for high-throughput applications, ideal for scientists conducting oligo screening, library generation, or custom batch synthesis. It accommodates one or two 384-well plates, and supports extensive oligonucleotide synthesis applications.
Key Features:
- Up to 768 samples for maximum throughput
- 2–200 nmol synthesis scale for flexible experiment design
- 16 unique protocols with 48 replicates each, supporting diverse workflows
- Ensures efficiency and precision for demanding laboratory needs.










