Description
Core Features Across All Models
- Accepts universal, standard, and modified resins
- Variable synthesis scales up to 10 µmol
- Fully programmable synthesis control
- Flexible, user-modifiable port assignments
- Supports 10+ backbone modifications
- Mixed-base coupling capability
- Compatible with all solid-phase synthesis methods
The Smallest Oligo Synthesizer in the World
The K&A S-4-LC is the world’s smallest DNA/RNA/LNA synthesizer—ideal for research labs that need rapid oligo production without sacrificing valuable bench space.
- 4 Column Positions
- 16 Bottle Positions
- Cycle time 2½ – 3 minutes for a full 4 column synthesis
- Dimensions (WxHxD): 25 x 25 x 30 cm
- Does not include trityl monitor
Minimal Consumption, Maximum Efficiency
The H-2 delivers the full feature set of the H-8 with fewer active column positions, making it ideal for applications that don’t require high-throughput synthesis. Designed as a seamless replacement for the ABI 392 or Expedite, it offers reliable performance while minimizing reagent use and waste.
- 2 columns
- 14 bottle positions
- Cycle time 2 – 2 ½ minutes for 2 column synthesis
- Online trityl monitor for all columns (all trityl collected)
- Dimensions (WxHxD): 25 x 40 x 40 cm
Large Scales, Small Footprint
The H-4-VLS is a modified H-8, engineered for synthesis scales exceeding 100 µmol—perfect for applications that require higher sample yields per run.
- 4 columns with double-spacing to allow for larger columns
- 18 bottle positions
- Variable synthesis scale up to 100+ µmol
- Online trityl monitor for all columns (all trityl collected)
- Dimensions (WxHxD): 25 x 40 x 40 cm
Premium Oligo Synthesizer
The H-8 represents the culmination of years of synthesis engineering, refined for modern research. Our flagship closed-column synthesizer delivers high-purity, long oligo synthesis.
- 8 columns
- 14 bottle positions
- Cycle time 4 – 4 ½ minutes for 8 column synthesis
- Online trityl monitor for all columns (all trityl collected)
- Dimensions (WxHxD): 25 x 40 x 40 cm
Every Modification Possible
Building on the popular H-8, the H-8 SE offers expanded flexibility for researchers experimenting with a wide variety of amidites and reagents.
- 8 columns
- 30 bottle positions
- Online trityl monitor for all columns (all trityl collected)
- Dimensions: 25cm x 60cm x 40cm
Large Scales in Throughput
The H-8-VLS is an H-8 SE variant capable of synthesis scales up to 100 µmol and beyond. Built for researchers who require maximum flexibility, it combines expanded capacity with all the core features of the H-8 SE:
- 8 columns
- 30 bottle positions
- Variable synthesis scale up to 100+ µmol
- Online trityl monitor for all columns (all trityl collected)
- Dimensions: 35 x 60 x 40 cm
Throughput Expansion
The H-16 retains the compact footprint of the H-8 SE while adding 8 column positions in place of 8 bottle positions.
- 16 columns
- 22 bottle positions
- Online trityl monitor for all columns (all trityl collected)
- Dimensions: 35 x 60 x 40 cm
A Freely Programmable Synthesizer
The H-32 retains all the features of its predecessors while scaling up to meet the demands of high-production facilities.
Its fully programmable delivery system allows users to exchange all columns for amidites or reagents, providing maximum flexibility and control.
- 32 column positions
- 11 positions
- Online trityl monitor for all columns (all trityl collected)
- Dimensions (WxHxD): 35 x 65 x 45 cm














